Five years after working triage during America’s terrible Day of Destruction, Philadelphian Dr. Ethan King wants nothing more for himself and his wife than a normal life. In the aftermath, however, life is anything but normal. The mysterious nerve gas unleashed during the nationwide terrorist attack has left its disturbing mark among the millions of victims, namely brain abnormalities in unborn children. These children, dubbed Inexorables, live up to their name: they are ruthlessly violent, irrepressibly psychopathic—and incurable. They kill without thought or remorse, and inflict torment on their victims with childish glee.
In his pursuit of a normal, peaceful life, Ethan tries as best he can to put these grim realities to the back of his mind. But one cold night, when he comes face to face with an abandoned Inexorable freezing to death in the snow, he must make a choice that could cost him everything, and unravel a thread of dark woven secrets. As he races to find a cure for whatever is creating a generation of doomed children, Ethan discovers that doing the right thing in an evil world is never as clear and easy as it seems.